Jennifer Rene’ Sims passed away on Tuesday, April 28, 2026, at NMMC-Tupelo after suffering a brain aneurism. She was 42 years old. Jennifer was born in Gulfport, MS. on Feb. 21, 1984, to the late Fred Sims and Myra Louise Medeirous. She attended Mooreville High School. Most of her working life, she cooked with her last employment at Huddle House on Veterans Avenue. Jennifer loved her children and grandchildren, enjoying time spent with them in their activities. She was a beloved stay at home Mom for much of her life.
There will be no formal services but the family will privately celebrate her life at a later date. Holland Funeral Directors-Tupelo is honored to be serving the family.
She leaves to mourn her passing, her children Jeffrey Caldwell, Dustyn and Nash Loden, Shelby Caldwell, Keri, Morgan and Airyonna Loden and Marina Loden; her brother Joshua Medeirous and her grandchildren, Meila and Miley Spencer, Aubrie Loden and Eleira Loden; aunt, Jackie, a special friend, Sylvia Loden; a special companion, Alex Graham and a host of other friends.
